A rivalry between iconic NFL quarterbacks and a huge prizefight highlight the sports calendar. Here's what to watch this weekend:

Friday, November 22

Towson at (2) Kansas

Phog Allen Field House, Lawrence, Kan.; 8 p.m. (ET) on ESPN3
Andrew Wiggins is a sensation for second-ranked Kansas (3-0). The heralded freshman has already provided a slew of dazzling plays just a few games into the season. The Towson Tigers (3-1) return the top five scorers from their 2012 team, but they'll be challenged by the talented and deep Jayhawks.

Saturday, November 23

(9) Texas A&M at (18) LSU

Tiger Stadium, Baton Rouge, La.; 3:30 p.m. (ET) on CBS
Eighteenth-ranked LSU (7-3) has won all five of its games at home this season, but the Tigers figure to have a tougher time against ninth-ranked Texas A&M (8-2) and reigning Heisman Trophy-winner Johnny Manziel. The Aggies quarterback is among the nation's leaders in passing yards, quarterback rating and touchdowns. LSU quarterback Zach Mettenberger is very good, too, having thrown for 20 touchdowns and 2,733 yards.

(19) Arizona State at (14) UCLA

Rose Bowl, Pasadena, Calif; 7 p.m. (ET) on Fox
Arizona State (8-2) will travel to No. 14 UCLA (8-2) with its Pac-12 South title hopes on the line. The 19th-ranked Sun Devils will clinch the division—and guarantee themselves a spot in the conference title game—with a victory over the Bruins. ASU wins with a stingy defense. Quarterback Brett Hundley and linebacker/running back Myles Jack lead the UCLA offense.

(8) Missouri at (24) Mississippi

Vaught-Hemingway Stadium, Oxford, Miss.; 7:45 p.m. (ET) on ESPN
Eighth-ranked Missouri (9-1) will attempt to stay in the Southeastern Conference title hunt when it visits No. 24 Mississippi (7-3). Quarterback James Franklin returns to the Tigers' starting lineup for the first time in four games. The Rebels are on a four-game win streak with quarterback Bo Wallace leading their offense.

(3) Baylor at (11) Oklahoma State

Boone Pickens Stadium, Stillwater, Okla.; 8 p.m. (ET) on ABC
Led by quarterback Bryce Petty and a high-scoring offense, undefeated, third-ranked Baylor (9-0) will attempt to stay in the national championship discussion when it travels to No. 11 Oklahoma State (9-1) on Saturday night. Cowboys QB Clint Chelf hopes to end the Bears' school-record 13-game winning streak.

Manny Pacquiao vs. Brandon Rios

CotaiArena, Macau, China; 9 p.m. (ET) on Pay-per-view
Manny Pacquiao (54-5-2, 38 KOs) will battle Brandon Rios (31-1-1, 22 KOs) in a 12-round welterweight fight. The veteran Pacquiao is a skilled fighter, but he may be showing signs of slowing down, which could open the door for the dangerous Rios. Other bouts on the card include Felix Verdejo vs. Duanaaymukdahan Petchsamuthr; Evgeny Gradovich vs. Billy Dib; and Andy Ruiz vs. Tor Hamer.

Sunday, November 24

Dallas Cowboys at New York Giants

MetLife Stadium, East Rutherford, NJ; 4:25 p.m. (ET) on Fox
Eli Manning and the surging New York Giants (4-6) bring a four-game win streak into Sunday's meeting against Dallas (5-5) and Tony Romo. The outcome could be pivotal in deciding the outcome of the NFC East race.

Denver Broncos at New England Patriots

Gillette Stadium, Foxborough, Mass.; 8:30 p.m. (ET) on NBC
Tom Brady leads his New England Patriots (7-3) against Peyton Manning and the Denver Broncos (9-1). Brady has a 9-4 lifetime record against Manning, and the Pats have home field advantage for the 14th meeting between these record-setting quarterbacks.

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